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Brian Appleby, MD

Brian Appleby, MD

  • Specialty: Psychiatry, Neurology, Psychiatry-Geriatric Psychiatry
    View Expertise
  • Primary Location: 3619 Park East Dr (7 mi.)
    Other Locations
  • Languages Spoken: English

Office Locations

UH Cleveland Foley ElderHealth Center (7 mi.)

3619 Park East Dr
Ste 109
Beachwood, OH 44122

216-464-6445

UH Cleveland Medical Center Lakeside 65 Research (0 mi.)

11100 Euclid Ave
Cleveland, OH 44106
216-844-4900

UH Cleveland Foley ElderHealth Center (7 mi.)

3619 Park East Dr
Ste 211
Beachwood, OH 44122
216-464-6215

Biography: Brian Appleby, MD

Expertise

  • Behavioral Neurology
  • Creutzfeldt-Jakob Disease
  • Dementia
  • Neuropsychiatry
  • Prion Diseases
  • Young-Onset Dementia

Titles

  • Associate Professor of Psychiatry, CWRU School of Medicine
  • Professor of Neurology, CWRU School of Medicine
  • Professor of Psychiatry, CWRU School of Medicine

Certifications & Memberships

  • Geriatric Psychiatry - American Board of Psychiatry and Neurology
  • Psychiatry - American Board of Psychiatry and Neurology
  • Certification in Behavioral Neurology & Neuropsychiatry, United Council for Neurologic Subspecialties

Education

Fellowship | Geriatric Psychiatry
Geriatric Psychiatry - THE JOHNS HOPKINS HOSPITAL (2007 - 2008)

Residency | Psychiatry
Psychiatry - THE JOHNS HOPKINS HOSPITAL (2004 - 2007)

Internship | Psychiatry
Psychiatry - Georgetown University Hospital (2003 - 2004)

Medical Education
Georgetown University School Of Medicine (2003)

Undergraduate
Goucher College (1999)

About

Brian Appleby, MD is a neuropsychiatrist at University Hospitals Cleveland Medical Center who treats and researches cognitive disorders. Dr. Appleby is an associate professor of neurology, psychiatry, and pathology at Case Western Reserve University and University Hospitals Cleveland Medical Center, the National Prion Disease Pathology Surveillance Center Director, and Medical Director of the Creutzfeldt-Jakob (CJD) Foundation. He is also chair of the Cleveland Chapter Alzheimer's Association Professional Advisory Board.  

Dr. Appleby received his medical degree from Georgetown University School of Medicine. He completed a psychiatry residency at The Johns Hopkins Hospital, where he also completed a geriatric psychiatry fellowship.

His clinical and research interests include prion diseases (e.g., Creutzfeldt-Jakob disease), frontotemporal lobar degeneration, and young-onset dementias.

 In his free time, he enjoys spending time with his family, computers, reading, Taekwondo, and Judo.

Research & Publications

Research Interests

Prion Disease, Frontotemporal lobar degeneration, Dementia

Featured Videos

Patient Experience Reviews

4.8 out of 5
- based on 59 Ratings
(5)
9/2/2025

He was pleasant. Reviewed my medical records. Ran through his exam and concluded with his assessment and plan for the future.

(5)
9/2/2025

Great!

(5)
8/1/2025

I love Dr. Appleby. He was the first one to figure out have to go to numerous neurologist as of what it is that I had a problem with so I always go to him. He's the best.

(5)
8/1/2025

They seem very concerned about my health

(5)
7/1/2025

Professional considerate comprehensive care

(5)
7/1/2025

Felt comfortable with this doctor.

(5)
6/1/2025

Dr. Appleby was knowledgeable in his explanation of what he thought was happening to me

(5)
6/1/2025

Our appts with Dr. Appleby are most informative and he has helped me so very very much. I also accompanied a special friend of mine to her appts with Dr. Appleby many years ago and she was very impressed by him as well. We think the world and more of him.

(5)
5/8/2025

Dr Appleby is a wonderful doctor.

(5)
5/8/2025

Good

(5)
3/2/2025

Dr.Appleby was very good, listened well.

(5)
3/2/2025

Very compassionate and knowledgeable about my concerns

(5)
2/2/2025

Dr Appleby is extremely nice and informative and listens and cares about his patients.

(5)
1/3/2025

Best provider I know for my condition!

(5)
1/3/2025

Great experience with Dr Appleby.

(5)
12/3/2024

Dr APPLEBY is knowledgeable and nice.

(5)
12/3/2024

My care provider is outstanding in all respects. I am fortunate to have such a capable person to deal with.

(5)
11/1/2024

All Good

(5)
11/1/2024

Dr Appleby was extremely caring and professional. Explanations were very thorough. So grateful to have seen him

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Industry Relationships

University Hospitals is committed to transparency in our interactions with industry partners, such as pharmaceutical, biotech, or medical device companies. At UH, we disclose practitioner and their family members’ ownership and intellectual property rights that are or in the process of being commercialized. In addition, we disclose payments to employed practitioners of $5,000 or more from companies with which the practitioners interact as part of their professional activities. These practitioner-industry relationships assist in developing new drugs, devices and therapies and in providing medical education aimed at improving quality of care and enhancing clinical outcomes. At the same time, UH understands that these relationships may create a conflict of interest. In providing this information, UH desires to assist patients in talking with their practitioners about industry relationships and how those relationships may impact their medical care.

UH practitioners seek advance approval for certain new industry relationships. In addition, practitioners report their industry relationships and activities, as well as those of their immediate family members, to the UH Office of Outside Interests annually. We review these reports and implement management plans, as appropriate, to address conflicts of interest that may arise in connection with medical research, clinical care and purchasing decisions.

View UH’s policy (PDF) on practitioner-industry relationships.

As of December 31, 2016, Brian Appleby did not disclose any Outside Relationships with Industry.